Evolution is the slow, intelligent increase in complexity via molecular processing over the aeons, starting with single cells and culminating in human beings.
Without evolution the development of the embryo would be impossible, because it too begins with a single cell and via the same intelligent molecular processing develops into an organism--for a human in only twelve weeks. That development is just evolution on very fast fast-forward. The process that was worked out over the aeons and perfected over the aeons can now take place at high speed.
Without the intelligent process of general evolution humans could not exist. Without the intelligent process of specific evolution humans could not be born. Both the evolution of all species across all time to produce humans at the apex, and the evolution of the individual human across the individual's time, are equally necessary.
Monday, July 14, 2008
Friday, July 4, 2008
ATP-ADP CYCLING NOW SIMULATED
Powerful software has for the first time simulated the detailed mechanics of the process in which ATP is cycled back to ATP after being converted to ADP when it releases a phosphate group (the process that provides the energy for most cellular functions).
Details in this ScienceDaily article.
Details in this ScienceDaily article.
Monday, June 30, 2008
Wednesday, June 25, 2008
CELLS ARE FULL OF SWITCHES
Surprise, surprise! Analysis with a supercomputer has found thousands of molecular switches in cells (see the full article in ScienceDaily).
But the researchers' assumption that 'evolution might stumble upon a switch' overlooks the obvious--that it processed its way to making a new one because it calculated a need for it.
Ditto the insertion, deletion and transfer of segments of DNA in organism. The processing over large timescales with low-power molecular-logic machines is slowly working things out.
Bio-molecular logic is a self-programming, self-modifying, self-improving, self-exploratory, self-analysing network of molecular machines beavering away at the base of an organism.
But the researchers' assumption that 'evolution might stumble upon a switch' overlooks the obvious--that it processed its way to making a new one because it calculated a need for it.
Ditto the insertion, deletion and transfer of segments of DNA in organism. The processing over large timescales with low-power molecular-logic machines is slowly working things out.
Bio-molecular logic is a self-programming, self-modifying, self-improving, self-exploratory, self-analysing network of molecular machines beavering away at the base of an organism.
Friday, June 6, 2008
RESEARCHERS WATCH RNA MACHINES WORKING
Researchers have reported that they are the first to observe the dynamic, ratchet-like movements of single ribosomal molecules in the act of building proteins from genetic blueprints--reports
ScienceDaily.
The astonishing accuracy and complexity of the system is ahown in another ScienceDaily article, which describes how it not only selects the right molecules but can reject wrong ones, even discriminating between ones that are little different.
Life's superb machinery at work.
ScienceDaily.
The astonishing accuracy and complexity of the system is ahown in another ScienceDaily article, which describes how it not only selects the right molecules but can reject wrong ones, even discriminating between ones that are little different.
Life's superb machinery at work.
Saturday, May 17, 2008
HUMAN INTERACTOME KEY TO UNIQUENESS
A new study indicates that the interactions between proteins, dubbed the human interactome in humans, could hold one of the keys to what makes organisms unique--not genetic makeup alone, reports ScienceDaily.
That should not be surprising. The processing power of a large network, both its processing power in real time and over a long period through many generations, is far greater than that of a smaller one. There will therefore be greater diversity in evolutionary development and in life's day-to-day actions and reactions.
That should not be surprising. The processing power of a large network, both its processing power in real time and over a long period through many generations, is far greater than that of a smaller one. There will therefore be greater diversity in evolutionary development and in life's day-to-day actions and reactions.
Tuesday, April 8, 2008
WHY DO WE SEARCH FOR BETTER WAYS?
Question: Why is the brain constantly learning and searching for better ways of doing things?
Answer: Because the intelligent biological molecules at the base of our physical being are doing the same thing.
The difference is that the brain, having the combined processing power of myriad molecules and neurons, does it at stupendous speed. They do it over the aeons, constantly perfecting cells, organs and organisms.
So they have two functions. In real time they process real-time matters, the low-level processing without which we cannot function. In aeon-time they process better organisms.
Answer: Because the intelligent biological molecules at the base of our physical being are doing the same thing.
The difference is that the brain, having the combined processing power of myriad molecules and neurons, does it at stupendous speed. They do it over the aeons, constantly perfecting cells, organs and organisms.
So they have two functions. In real time they process real-time matters, the low-level processing without which we cannot function. In aeon-time they process better organisms.
Thursday, March 27, 2008
SILENT GENES ARE WHISPERING
Genes previously thought to be off are actually functioning at a low level, with unknown effect, reports ScienceDaily.
Monday, March 24, 2008
LOGICAL DEVICES AND LIFE
LOGICAL DEVICES
The atom is a logical device. It is built of various particles of energy that have a logical relationship with each other and a logical influence on each other. Collectively they form a logically functional unit from whtih larger logically functional units can be built. The logical power of the super-structures (the molecules) increases exponentially with the number of units they contain.
Some types of atoms are particularly well-suited to forming powerful molecules, notably carbon, hydrogen, oxygen, phosphorus, etc.
Life is the ultimate logical construct.
The atom is a logical device. It is built of various particles of energy that have a logical relationship with each other and a logical influence on each other. Collectively they form a logically functional unit from whtih larger logically functional units can be built. The logical power of the super-structures (the molecules) increases exponentially with the number of units they contain.
Some types of atoms are particularly well-suited to forming powerful molecules, notably carbon, hydrogen, oxygen, phosphorus, etc.
Life is the ultimate logical construct.
Tuesday, February 26, 2008
MORE EVIDENCE OF THE BIO-LOGICAL HIEARCHY
These articles in ScienceDaily, one about molecular communication the other about cellular communication, show that we are starting to zero in on the details of basic biological functioning.
'Biological' turns out to be a nice pun. It is indeed the logical functioning of life: bio-logical.
We have also managed to film an electron going about its business.
Perhaps we shall one day be able to figure out how the hierarchy of the logic of life works, all the way up from the electron, or lower, right up to the intelligent molecular machines and the networks of them on which our cells are founded.
'Biological' turns out to be a nice pun. It is indeed the logical functioning of life: bio-logical.
We have also managed to film an electron going about its business.
Perhaps we shall one day be able to figure out how the hierarchy of the logic of life works, all the way up from the electron, or lower, right up to the intelligent molecular machines and the networks of them on which our cells are founded.
Tuesday, February 12, 2008
FOOD CHANGES US
We are what we eat, as this study shows. The biolmolecular logic is changed by diet, clearly one of the factors that it adapts to as it processes over the aeons.
DANCING WATER CHANGED BY PROTEIN FOLDING
This blog speculated in an earlier posting that water might be used by proteins for more than just lubrication, that there might be an intelligent use. Now research using terahertz spectroscopy gives some evidence for that. But even without the empirical science it is reasonable to think that the modifications described are not meaningless accidents, so there may well be a signalling aspect.
Saturday, February 2, 2008
THE MOLECULAR PROCESSING OF EVOLUTION
As the organism grows and learns, so do its biomolecules, adjusting at the fundamental level to its behaviour and interaction with the environment.
Thus the proto-bird flaps its proto-wings to help speed it from a predator, and its molecules begin the long, multi-generational changes to feathers, bone, etc., and creation develops in defiance of the Second Law of Thermodynamics. Organisation, driven by fundamental intelligence--a myriad of smart nanonmachines--triumphs over disorganisation.
The slow calculation of the aeons, ever filtering and improving, generation after generation, just as the brain processes thoughts and arrives at the best conclusions, but far slower, because the processing power is far less.
A feedback-loop, back and forth between the basic molecular machines and the full organism, IS ever refining, adapting, living...
Thus the proto-bird flaps its proto-wings to help speed it from a predator, and its molecules begin the long, multi-generational changes to feathers, bone, etc., and creation develops in defiance of the Second Law of Thermodynamics. Organisation, driven by fundamental intelligence--a myriad of smart nanonmachines--triumphs over disorganisation.
The slow calculation of the aeons, ever filtering and improving, generation after generation, just as the brain processes thoughts and arrives at the best conclusions, but far slower, because the processing power is far less.
A feedback-loop, back and forth between the basic molecular machines and the full organism, IS ever refining, adapting, living...
Thursday, January 10, 2008
MAGNETIC CONTROL OF MOLECULAR MACHINES
This ScienceDaily story details an exciting, new, magnetic way of controlling cellular molecules. The effect is the same as when drugs or other molecules bind to the same molecules.
The mechanical method has exactly the same effect as the 'chemical' one. That could only happen if the cellular molecules are machines. QED.
The mechanical method has exactly the same effect as the 'chemical' one. That could only happen if the cellular molecules are machines. QED.
Wednesday, January 9, 2008
THE LOGIC AND TRUTH OF BEING
We are founded on logic, on the truth of our being. When we betray logic and truth we not only betray what we are we also damage its fundamental functioning and structure, and the result is physical and mental unease or disease.
MACHINES OF BEING
Body molecules--DNA, proteins, etc--are machines, not reagents.
So traditional pharmaceuticalists are like sculptors who think they are modifying sculptures but are actually blundering mechanics trying to modify an engine without realising that it is an engine, have never seen one running, and have no notion that it is or of how it is.
So traditional pharmaceuticalists are like sculptors who think they are modifying sculptures but are actually blundering mechanics trying to modify an engine without realising that it is an engine, have never seen one running, and have no notion that it is or of how it is.
Tuesday, January 8, 2008
THE PHYSICAL AND SPIRITUAL MEETING-POINT
The organism senses and functions, at the highest level, as an organism. Below that are the senses and functions of the organs, below that are the senses and functions of the structures within organs, below that are the senses and functions of the cellular networks, below that are the senses and functions of the cells, below that are the senses and functions of the molecular networks, below that are the senses and functions of the molecules, which are made of atoms, which have their own fundamental 'senses and functions,' the actions and reactions we call physics and basic chemistry.
On fundamental atomic 'sense' is built a higher level of sense, the molecular; upon that is built a higher level, the molecular networks; upon that is built a higher level, the cellular; upon that is built a higher level, the sub-structures of the organ; upon that is built a higher level, the organic; upon that is built the highest level, that of the organism.
In short, the intelligence of the organism is built on molecular intelligence, which is built on the natural logic of the atom. The intelligence and functioning of the organism is founded on molecular intelligence and its interaction with the organism through the ascending intelligence hierarchy.
In, around and under that is the quantum world, the world of particles, where, as Einstein put it, there is 'spooky action at a distance', quantum entanglement. Particles can be 'aware' of and 'in contact' with others, synchronising instantly, constantly, irrespective of distance. That defies logic and physics, it is incomprehensible to the reasonable laws of the physical--because they are no longer in operation. It must, therefore, be the level of the spiritual. Thus in our desire for ever deeper knowledge of the physical universe we have dug down so far that we have gone out of it altogether, and found to our surprise or chagrin that the whole thing is founded on the spiritual. We have found the point at which spirit and flesh divide. Physics is at loss to explain anything at that level because it just is, existing and functioning in the eternal now, the realm of the spiritual.
As Time magazine said years ago, 'The scientists, after slogging up the mountain of knowledge for centuries, arrive at the top to find the theologians sitting there waiting for them.'
More light may be shed on the same point by this ScienceDaily report in August 2008. As an unknown amateur poet once said: 'In and out of things that seem are dancing things that are.'
---------
The level above the spiritual, the molecular, is where all our physical actions start. The mechanism of feeling thirsty, for example, can be seen as having as its fundamental cause the fact that the nanomachines we call protein molecules are lubricated by water, and that its attendant 'minuet' is also vital to their proper formation. So when there is insufficient water for all that to happen as it should it is the protein molecules that will notice it first. That message passed up the chain causes you to head for the tap.
(It also seems reasonable to think that that 'water network' is also used in intermolecular communication, using water molecules as a choregraphed pigeon-post. The dance set up by one molecule used to interface with the dance of the next one, like so many ballerinas passing a particular step across the stage, or so many bees signalling to their peers by their dance where they should fly to gather nectar.)
(Copied from a posting to my EStar blog dated the 5th of December 2007.)
On fundamental atomic 'sense' is built a higher level of sense, the molecular; upon that is built a higher level, the molecular networks; upon that is built a higher level, the cellular; upon that is built a higher level, the sub-structures of the organ; upon that is built a higher level, the organic; upon that is built the highest level, that of the organism.
In short, the intelligence of the organism is built on molecular intelligence, which is built on the natural logic of the atom. The intelligence and functioning of the organism is founded on molecular intelligence and its interaction with the organism through the ascending intelligence hierarchy.
In, around and under that is the quantum world, the world of particles, where, as Einstein put it, there is 'spooky action at a distance', quantum entanglement. Particles can be 'aware' of and 'in contact' with others, synchronising instantly, constantly, irrespective of distance. That defies logic and physics, it is incomprehensible to the reasonable laws of the physical--because they are no longer in operation. It must, therefore, be the level of the spiritual. Thus in our desire for ever deeper knowledge of the physical universe we have dug down so far that we have gone out of it altogether, and found to our surprise or chagrin that the whole thing is founded on the spiritual. We have found the point at which spirit and flesh divide. Physics is at loss to explain anything at that level because it just is, existing and functioning in the eternal now, the realm of the spiritual.
As Time magazine said years ago, 'The scientists, after slogging up the mountain of knowledge for centuries, arrive at the top to find the theologians sitting there waiting for them.'
More light may be shed on the same point by this ScienceDaily report in August 2008. As an unknown amateur poet once said: 'In and out of things that seem are dancing things that are.'
---------
The level above the spiritual, the molecular, is where all our physical actions start. The mechanism of feeling thirsty, for example, can be seen as having as its fundamental cause the fact that the nanomachines we call protein molecules are lubricated by water, and that its attendant 'minuet' is also vital to their proper formation. So when there is insufficient water for all that to happen as it should it is the protein molecules that will notice it first. That message passed up the chain causes you to head for the tap.
(It also seems reasonable to think that that 'water network' is also used in intermolecular communication, using water molecules as a choregraphed pigeon-post. The dance set up by one molecule used to interface with the dance of the next one, like so many ballerinas passing a particular step across the stage, or so many bees signalling to their peers by their dance where they should fly to gather nectar.)
(Copied from a posting to my EStar blog dated the 5th of December 2007.)
BACTERIA ARE SMARTER THAN PEOPLE
They also show us the way to a true democracy.
The September/October 2006 issue of Update, the magazine for members of the New York Academy of Sciences, has a piece headed Microbial Chatter, How Bacteria Talk to Each Other, which outlines the researches of Bonnie Hassler, a molecular biologist at Princeton University and the Howard Hughes Medical Institute.
'She has found that bacteria like to live in complex multi-species communities and their ability to communicate and co-operate is essential to their survival,' says the magazine. Amongst other abilities, they are 'multilingual' (via signalling molecules called auto-inducers), and they have a communications system called 'quorum sensing' in which the majority rules. A single bacteria expressing what might be called an auto-inducer opinion cannot persuade group action; that happens only when a large number express it in unison. There are three main types of auto-inducers. One of them enables cross-species communications: 'An example of this ability for mixed-species consortia to talk among themselves is evident on our teeth: 600 species are there every morning in precisely the same organisation as the night before. The only way they can build their complicated biofilms is to know precisely what other cells are out there and to use the information to function effectively as a working conglomerate.'
Meanwhile, in the brains a few centimetres above those teeth there is touching faith in the notion that our system of government is a democracy, that it truly is 'government of the people, by the people, for the people', when it is nothing but an elected dictatorship--it is government of the people, by a few people, for some people. The bacteria have true a democracy. Every bug has an auto-inducer voice, every voice counts, and the action of the group is decided by the majority in unison. A molecular opinion expressed by only a few bugs is ignored.
Poor people. How sad! They have less organisational sense than the bugs on their teeth.
(Copied from a posting to my EStar blog dated the 9th of October 2006.)
Footnote posting (2nd of May 2008): As this article in ScienceDaily shows, the phenomenon of 'quorum-sensing' as it is called can now be used to tell staph biofilms to go away. Rather like telling politicians ditto. Would that they would take the same kind of notice...
The September/October 2006 issue of Update, the magazine for members of the New York Academy of Sciences, has a piece headed Microbial Chatter, How Bacteria Talk to Each Other, which outlines the researches of Bonnie Hassler, a molecular biologist at Princeton University and the Howard Hughes Medical Institute.
'She has found that bacteria like to live in complex multi-species communities and their ability to communicate and co-operate is essential to their survival,' says the magazine. Amongst other abilities, they are 'multilingual' (via signalling molecules called auto-inducers), and they have a communications system called 'quorum sensing' in which the majority rules. A single bacteria expressing what might be called an auto-inducer opinion cannot persuade group action; that happens only when a large number express it in unison. There are three main types of auto-inducers. One of them enables cross-species communications: 'An example of this ability for mixed-species consortia to talk among themselves is evident on our teeth: 600 species are there every morning in precisely the same organisation as the night before. The only way they can build their complicated biofilms is to know precisely what other cells are out there and to use the information to function effectively as a working conglomerate.'
Meanwhile, in the brains a few centimetres above those teeth there is touching faith in the notion that our system of government is a democracy, that it truly is 'government of the people, by the people, for the people', when it is nothing but an elected dictatorship--it is government of the people, by a few people, for some people. The bacteria have true a democracy. Every bug has an auto-inducer voice, every voice counts, and the action of the group is decided by the majority in unison. A molecular opinion expressed by only a few bugs is ignored.
Poor people. How sad! They have less organisational sense than the bugs on their teeth.
(Copied from a posting to my EStar blog dated the 9th of October 2006.)
Footnote posting (2nd of May 2008): As this article in ScienceDaily shows, the phenomenon of 'quorum-sensing' as it is called can now be used to tell staph biofilms to go away. Rather like telling politicians ditto. Would that they would take the same kind of notice...
ONE NEURON IS A LOT OF POWER
Oh, surprise, surprise! They have just discovered that a single neuron has a lot of processing power, as this BBC report outlines.
This blogger has been saying for some time that the fundamental processing power in the brain, and in the entire body, is molecular. In each neuron there are billions of molecules. Small wonder that different synapses in the same neuron can be processing different bits of information.
The subconscious is far more 'sub'--far more fundamental--than we thought.
This blogger has been saying for some time that the fundamental processing power in the brain, and in the entire body, is molecular. In each neuron there are billions of molecules. Small wonder that different synapses in the same neuron can be processing different bits of information.
The subconscious is far more 'sub'--far more fundamental--than we thought.
INSIGHT ON THE WORKING OF THE BRAIN NOW PROVED
This blog has from time to time gone right off the topic of energy to publish ideas about DNA, cellular proteins and the detailed workings of neurons. It is gratifying to see that empirical research has now shown those ideas to have been correct--see this report in
Science Daily.
The point was underlined by another report that came out a month later, also in Science Daily.
For the earlier postings click here, and here, and here.
(Copied from a posting to my EStar blog dated the 18th of August 2007.)
Science Daily.
The point was underlined by another report that came out a month later, also in Science Daily.
For the earlier postings click here, and here, and here.
(Copied from a posting to my EStar blog dated the 18th of August 2007.)
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